Your doctor may may provide you with prescription migraine medication such as nonsteroidal anti-inflammatory drugs (NSAIDs), which are considered a second-line preventative treatment for migraine. They are often recommended when pre-existing health conditions make first-line treatments inadvisable, or when first-line treatments just aren’t effective. They may also be useful to those who can’t tolerate the side effects of antiepileptics, beta-blockers and antidepressants..
NSAID drugs are effective migraine medication for women who suffer from menstrual migraine. The drugs are usually started about seven days prior to the start of the menstrual period and taken two to three times daily, depending on the drug and dosage.
NSAIDs used for migraine prevention include aspirin (or acetylsalicylic acid), naproxen sodium (Aleve), and ibuprofen (Advil). Although many NSAIDs are sold as over-the-counter drugs, you should work with your doctor to determine what kind and dosage makes the best migraine medication for your particular situation.
Some NSAIDs can increase your sensitivity to the sun, so avoid prolonged sun exposure and use sunscreen when taking them. You may also suffer from fluid retention, nausea, vomiting, diarrhea, heartburn and fatigue.
Be sure to avoid alcohol as this will increase your risk of stomach bleeding. If you take lithium, methotrexate, or any diuretics, NSAIDs can impact the therapeutic action of these drugs. Certain NSAIDs can aggravate your health condition if you usffer from stomach ulcers, asthma, heart disease, kidney or liver problems.
Children and teenagers with flu-like symptoms should not take aspirin or nonaspirin salicylates because it can increase the risk of developing Reyes Syndrome which could be fatal and cause serious damage to the liver, brain and other organs. Younger migraineurs are likely to be better off taking Butterbur pills instead. NSAIDs inhibit platelet function, they should be avoided by people who take other blood-thinning drugs or who are scheduled for surgery.